Studying the Expressed Genes of Breast Cancer Tumors

By analyzing which animal models of breast cancer best compare to human cases, Eran Andrechek, an assistant professor of physiology, is hoping to overcome one of the most significant barriers in treating the deadly disease: The genetic complexity of the tumors themselves. Andrechek has received a $450,000 grant from the Susan G. Komen for the Cure [...]

Symposium on Transcriptional Dynamics, Evolution, and Systems Biology

MSU is hosting the biannual Summer Symposium on Transcriptional Dynamics, Evolution, and Systems Biology in East Lansing, Michigan, July 22 − 24, 2011. The symposium will cover three major areas of intersection between computational biology and modeling interface with transcriptional control. The first topic is the potential for molecular dynamics simulation to extend the understanding [...]

Research Pinpoints Genetic Pathways Involved in Breast Cancer

Physiology Assistant Professor Eran Andrechek has research published in the journal Cancer Researchthat uncovers a role for several members of the E2F family of genes, which control cell division and growth. The findings uncover a genetic pathway that affects the development of breast cancer. Read more…

Developmental Genes Have More Than One Way to Stop

Biochemistry Professor David Arnosti has research published in this week’s Current Biology discussing how specific repressor proteins slow genes during development and how the process is comparable to slowing down a car. Read more…

Next Gen Research Provides Clues in Gene Mysteries

Big science has always required big tools – from super colliders that reveal the forces binding atomic nuclei to super sequencers that reveal the genes in a cell’s nucleus. The complexities and costs of these latest tools involved in 21st century science make it impractical to have them in individual laboratories. Instead, these tools are [...]

Increase of Beta-Carotene in Corn Means Improvement for Human Health

Scientists have uncovered the molecular basis of natural genetic variation for improving beta-carotene (provitamin A) in corn, a finding that can lead to combating Vitamin A deficiency and improved human health in the developing world. An international collaboration of scientists, including MSU biochemistry professor Dean DellaPenna, published their findings of the rare genetic variation in [...]

Biochemistry & Plant Biology part of $6M NIH GO Grant

Biochemistry Professor Dean Della Penna and Plant Biology Associate Professor Robin Buell are part of a $6 million NIH Grand Opportunities grant to understand exactly which genes are involved in the synthesis of medicinal chemicals in several plants — clearing the way for cheaper and more effective ways to produce drugs. Read more>>

Gene expression group marks 10 years

New technology is changing the way scientists ask questions about gene expression in order to battle disease. Helping keep MSU on the forefront is the Gene Expression in Disease and Development group, a community of scholars focused on the mechanisms of gene regulation. The group is marking its 10th anniversary with a ceremony at 2:00 pm on Sept. 18 [...]

Metagenomics research in the classroom

A new microbiology class at MSU’s Kellogg Biological Station this summer will teach students next generation sequencing techniques as they collaborate with an ongoing research project. Microbiology students will be immersed in the study of genomics of communities for two weeks as part of MMG 490: Microbial Metagenomics. The class is part of a new [...]

Videos on transcriptional regulation and systems biology

The Gene Expression in Development and Disease Initiative has made available videos of the presentations from this summer’s Symposium on Transcriptional Regulation and Systems Biology. If you missed the symposium or want to review the presentations, visit the symposium website.